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One of the most fascinating Biology Topics is the study of the brain and behavior.
How Does the Blood Circulatory System Work? What is Heart Beat and How to Measure Blood Pressure?
The organ system of human beings (and other animals) which is responsible for the transport of materials inside the body is called the circulatory system. The various organs of the circulatory system in humans are the Heart, Arteries, Veins, and Capillaries. Blood is also considered a part of the circulatory system. So, the human circulatory system consists of the heart, arteries, veins, capillaries, and blood. In the circulatory system, the heart acts as a pump to push out blood. The arteries, veins, and capillaries act as pipes (or tubes) through which the blood flows. These tubes which carry blood are called blood vessels. Thus, there are three types of blood vessels in the human body: arteries, veins, and capillaries. We will now describe all the parts of the circulatory system in detail.
The heart is roughly triangular in shape. It is made of a special muscle called cardiac muscle. The size of our heart is about the same as our ‘clenched fist’. The heart has four compartments called ‘chambers’ inside it. The upper two chambers of the heart are called the atria (singular atrium), and the lower two chambers of the heart are called the ventricles. The two atria receive blood from the two main veins. And the two ventricles transport blood to the entire body and the lungs. The left atrium is connected to the left ventricle through a valve V1.
Similarly, the right atrium is connected to the right ventricle through another valve V2. These valves prevent the backflow of blood into the atria when the ventricles contract to pump blood out of the heart to the rest of the body. This is because when the ventricles contract, the valves V1 and V2 close automatically so that the blood may not go back into the atria. The job of the heart is to pump blood around our body. All the atria and ventricles of the heart contract and relax (expand) at appropriate times and make the heart behave like a pump. Since ventricles have to pump blood into various organs with high pressure, they have thicker walls than atria. A sheath of tissue called ‘pericardium’ protects the muscular heart. The chambers of the heart are separated by a partition called a septum.
The arteries, veins, and capillaries are kind of thin pipes (or tubes) through which blood flows in the body. Arteries, veins, and capillaries are called blood vessels. Arteries are the thick-walled blood vessels that carry blood from the heart to all the parts of the body. Arteries have thick walls because blood emerges from the heart under high pressure. Arteries are found in the whole of our body. The main artery (called the aorta) is connected to the left ventricle of the heart through a valve V3. The main artery carries oxygenated blood from the left ventricle to all body parts (except the lungs). Another artery called the pulmonary artery is connected to the right ventricle of the heart through another valve V4. The pulmonary artery carries deoxygenated blood from the right ventricle to the lungs.
The capillaries are thin-walled and extremely narrow tubes or blood vessels which connect arteries to veins. Thus, the capillaries are in-between the arteries and veins. The blood from arteries enters the capillaries in the body. Every living cell of our body is close to a capillary. The walls of capillaries are only one cell thick. The various dissolved substances (like oxygen, food, etc.) present in the blood pass into the body cells through the thin walls of the capillaries. At the same time, the waste substances (like carbon dioxide) formed in the cells enter into capillaries. Thus, the exchange of various materials like oxygen, food, carbon dioxide, etc., between the blood and the body cells takes place through capillaries. The other end of the capillaries is joined to some wider tubes called veins. The deoxygenated blood (or dirty blood) coming from the capillaries enters into veins.
Arteries are joined to veins through a network of very thin blood vessels called capillaries. Food and oxygen go from blood into body cells through capillaries. Waste materials (like carbon dioxide) go from body cells into the blood through capillaries.
This photo of capillaries was taken using a modem microscope. See how thin the capillaries are.
Veins are the thin-walled blood vessels that carry blood from all the parts of the body back to the heart. Veins do not need thick walls because the blood flowing through them is no longer under high pressure. Veins have valves in them that allow the blood in them to flow in only one direction (toward the heart). The valves prevent the backflow of blood in veins. Veins are also found in the whole of our body. The pulmonary vein is connected to the left atrium of the heart.
The pulmonary vein carries oxygenated blood from the lungs back to the heart. There is also a main vein (called the vena cava). The main vein is connected to the right atrium of the heart. The main vein carries deoxygenated blood from all the parts of the body (except lungs), back to the heart. Please note that the main difference between an artery and a vein is that an artery carries blood from the heart to the body organs whereas a vein carries blood from the body organs back to the heart.
We have just studied that the heart is a kind of pump that pumps blood around our body continuously, without stopping. Actually, the heart is not a single pump. The heart is really a double pump. The left side of the heart (left atrium and left ventricle) acts as one pump which pumps blood into the whole body, except the lungs. The right side of the heart (right atrium and right ventricle) acts as another pump that pumps blood only into the lungs. We can see from the Figure that the left side of the heart is completely separated from the right side by a partition called a septum. So, the two pumps in the heart work independently. The separation of the left and right sides of the heart is necessary to prevent the mixing of the oxygenated blood on the left side with the deoxygenated blood on the right side.
Before we describe the circulation of blood in the human body with the help of a diagram, we should keep the following two points in mind: First that the blood circulates in our body in two forms: oxygenated blood and deoxygenated blood. The blood carrying oxygen in it is called oxygenated blood. We get oxygenated blood in the lungs where the fresh oxygen of air passes into the blood. The blood has no oxygen in it is called deoxygenated blood.
Deoxygenated blood is formed in all the organs of the body (except the lungs). This is because when oxygenated blood passes through the organs of the body, the body cells use up their oxygen and make them deoxygenated. The deoxygenated blood, however, carries carbon dioxide in it (which is produced during respiration in body cells). The second point to remember is that when blood circulates in the body, then it supplies oxygen, digested food, and other chemicals (like hormones) to all the cells of the body. It also carries back waste products like carbon dioxide, etc., from the body cells.
The heart beats non-stop all the time. The heartbeat is due to the rhythmic contraction and relaxation of the heart muscles that comprise the atria and the ventricles. Please note that the two atria (left atrium and right atrium) contract together and relax together. Similarly, the two ventricles (left ventricle and right ventricle) contract together and relax together. The contraction of two atria is immediately followed by the contraction of the two ventricles.
The heart beats (or beating of the heart) circulates the blood in the human body. We will now describe the circulation of blood in the human body with the help of a highly simplified diagram.
1. When the muscles of all four chambers of the heart are relaxed, the pulmonary vein brings the oxygenated blood (oxygen-carrying blood) from the lungs into the left atrium of the heart (see step 1 in Figure).
2. When the left atrium contracts, the oxygenated blood is pushed into the left ventricle through valve V1 (see step 2 in Figure).
3. When the left ventricle contracts, the oxygenated blood is forced into the main artery called the ‘aorta’ (see step 3 in Figure). This main artery then branches into smaller arteries which go into different body organs (except the lungs). The smaller arteries (called arterioles) further branch into capillaries (The smaller arteries and capillaries have not been shown in Figure to keep the diagram simple).
4. The main artery carries blood to all the organs (or parts) of the body like the head, chest, arms, stomach, intestines, liver, kidney, trunk, and legs (except the lungs). When the oxygenated blood passes through the capillaries of the body organs, then it gives oxygen to the body cells. Since the blood loses oxygen here, we say that the blood has been deoxygenated. The blood also gives the digested food and other dissolved materials to the body cells. At the same time, carbon dioxide produced as waste material during respiration enters into the blood. The deoxygenated blood (carrying carbon dioxide) from the body organs enters into the main vein called the vena cava. The main vein carries the deoxygenated blood to the right atrium of the heart (see step 4 in Figure).
5. When the right atrium contracts, deoxygenated blood is pushed into the right ventricle through valve V2 (see step 5 in Figure).
6. And when the right ventricle contracts, the deoxygenated blood is pumped into the lungs through the pulmonary artery (see step 6 in Figure). In the lungs, deoxygenated blood releases its carbon dioxide and absorbs fresh oxygen from the air. So, the blood becomes oxygenated again. This oxygenated blood is again sent to the left atrium of the heart by the pulmonary vein for circulation in the body.
This whole process is repeated continuously. In this way, the blood keeps on circulating in our body without stopping due to which all the body parts keep on getting oxygen, digested food, and other materials all the time. The blood circulation also keeps on removing waste products formed in the cells of body.
The blood circulatory system in human beings is an example of double circulation. This can be explained as follows: A circulatory system in which the blood travels twice through the heart in one complete cycle of the body is called double circulation. In the human circulatory system, the pathway of blood from the heart to the lungs and back to the heart is called pulmonary circulation; and the pathway of blood from the heart to the rest of the body and back to the heart is called systemic circulation. These two types of circulation taken together make double circulation.
The animals such as mammals (including human beings), and birds have a four-chambered heart (which consists of two atria and two ventricles). In a four-chambered heart, the left side and right side of the heart are completely separated to prevent the oxygenated blood from mixing with deoxygenated blood. Such a separation allows a highly efficient supply of oxygen to the body cells which is necessary for producing a lot of energy. This energy is useful in warm-blooded animals (like mammals and birds) which have high energy needs because they constantly require energy to maintain their body temperature. All the animals having four-chambered hearts have double circulation in which the blood passes through the heart ‘twice’ in one complete cycle of the body.
The animals such as amphibians and many reptiles are cold-blooded animals whose body temperature depends on the temperature in the environment. They do not need energy to maintain their body temperature and hence their requirement of energy is less. The amphibians (like frogs) and reptiles (like lizards) have a three-chambered heart (which consists of two atria and one ventricle). Due to incomplete division within their heart, the oxygenated and deoxygenated blood mix to some extent in amphibians and reptiles. This reduces the production of energy. The amphibians and reptiles have, however, a double circulation that delivers blood to the lungs and the rest of the body, respectively.
Mammals (including human beings and birds like this hen) have 4-chambered hearts.
Amphibians (like this frog) have a 3-chambered heart.
Reptiles (like this lizard) also have a 3-chambered heart.
Fish has a 2-chambered heart.
The fish has a two-chambered heart (which consists of one atrium and one ventricle). The fish does not have lungs, it has gills to oxygenate blood. In a fish, the heart pumps deoxygenated blood to the gills. Oxygenation of blood takes place in the gills. The oxygenated blood from the gills is supplied to the body parts of the fish where oxygen is utilized and carbon dioxide enters into it making it deoxygenated. This deoxygenated blood returns to the heart to be pumped into the gills again. The flow of blood in a fish is called single circulation because the blood passes through the heart of the fish only once in one complete cycle of the body.
Heart Beats
The heart pumps blood into our arteries by contracting. When the heart contracts, it becomes smaller in size and pushes the blood into the main artery with great force. Then the heart relaxes (comes back to its original size) and gets filled up with blood from the pulmonary vein. In this way, the heart keeps on contracting and relaxing, again and again, to pump blood into the body continuously. One complete contraction and relaxation of the heart is called a heartbeat. The heart usually beats about 70 to 72 times in a minute when we are resting. This means that the heart pumps out blood to the arteries about 70 to 72 times per minute.
We can feel our heartbeats if we place our hand on the chest, just above the heart region.
A stethoscope magnifies the sound of heartbeats so that they can he heard clearly.
A doctor listens to our heartbeats by using a stethoscope. This gives the doctor an idea of the condition of our heart.
We can feel our heartbeats if we place our hands on the chest just above the heart region. A doctor listens to our heartbeats by using an apparatus called a stethoscope. The stethoscope magnifies the sound of heartbeats so that the doctor can hear the heartbeats clearly.
Though the average number of heartbeats of a person at rest is about 70 to 72 per minute the number of heartbeats increases too much after a physical exercise or when a person is excited. For example, if we count our heartbeats after running for a while, we will find them to be more than 100 per minute. The heart beats faster during and after an exercise because the body needs more energy under these conditions. The faster beating of the heart pumps blood more rapidly to the body organs which supplies more oxygen to the body cells for rapid respiration to produce more energy. The heartbeats can be counted easily by counting the pulse.
How to check your Pulse?
Every time the heart beats, blood is forced into arteries. This blood makes the arteries expand a little. The expansion of an artery each time the blood is forced into it is called a pulse. Each heartbeat generates one pulse in the arteries, so the pulse rate of a person is equal to the number of heartbeats per minute. Since the heart beats about 70 to 72 times per minute, therefore, the pulse rate of an adult person while resting is 70 to 72 per minute. Thus, the pulse rate is the same as the heart rate. Just like heartbeats, the pulse rate of a person is higher after a physical exercise or when a person is excited.
Most of our arteries lie deep inside our body and hence cannot be used to feel the pulse. But at some places in our body like the wrist, temple, and neck, the arteries are close to the surface of the skin and pass over bones. So, we can feel the pulse at the wrist, temple, and neck by pressing the artery lightly with our fingertips. The pulse is traditionally taken above the wrist. We can feel our own pulse and find the pulse rate as follows:
The pulse can be felt with fingers placed gently on arteries at the wrist. We place the first two fingers (index finger and middle finger) of our right hand on the inner side of our left wrist and press it gently. We will feel some waves touching our fingers. These waves are the pulse. We can count the number of such waves (or thumpings) in one minute by using a watch. This will give us the pulse rate (per minute).
We usually see the doctor taking the pulse rate of a patient by keeping his fingers on the wrist of the patient and at the same time looking into his watch. Doctors can tell by counting the pulse rate and listening to heartbeats whether a person is well or not. This is because the pulse rate and heartbeats change according to the condition of our heart.
Understanding Blood Pressure Readings
The pressure at which blood is pumped around the body by the heart is called blood pressure. The blood pressure of a person is always expressed in the form of two values called ‘systolic pressure’ and ‘diastolic pressure’. In order to understand this, we should first know the meaning of ‘systole’ and ‘diastole’. The phase of the heartbeat when the heart contracts and pumps the blood into arteries is called ‘systole’. And the phase of the heartbeat when the heart relaxes (or expands) and allows the chambers to fill with blood is called ‘diastole’.
The maximum pressure at which the blood leaves the heart through the main artery (aorta) during the contraction phase, is called the systolic pressure. This high pressure in the main artery maintains a steady flow of blood in all the arteries toward the capillaries. The minimum pressure in the arteries during the relaxation phase of the heart is called the diastolic pressure. The value of diastolic pressure is always lower than that of the systolic pressure. The blood pressure of a person is expressed in terms of millimeters of mercury (which is written as mm Hg). The normal blood pressure values are Systolic pressure: 120 mm Hg, Diastolic pressure: 80 mm Hg. This is usually written as 120/80
The blood pressure values vary from person to person and from time to time. They also vary with age. For example, a young person may have a blood pressure of 110/75 but at the age of 60 years, it could be 145/90. High blood pressure is called hypertension. High blood pressure is caused by the constriction (narrowing) of very small arteries (called arterioles) which results in increased resistance to blood flow. Very high blood pressure can lead to rupture of an artery and internal bleeding.
How to measure Blood Pressure
Blood pressure is measured by using an instrument called a sphygmomanometer. Two readings of blood pressure are taken: systolic pressure (when the heart is contracting and pumping out blood), and diastolic pressure (when the heart relaxes and fills with blood). The various steps in measuring the blood pressure of a person are as follows:
(i) A rubber cuff (which is a flat rubber tube) is wrapped around the person’s arm, The rubber cuff is inflated by pumping air into it to give a pressure of about 200 mm Hg to the brachial artery (which runs down the arm). This pressure can be seen on the scale of the instrument sphygmomanometer. If a stethoscope is now placed on the artery of the arm, no sound is heard through it.
Measuring blood pressure by using a mercury sphygmomanometer.
(ii) With the stethoscope still placed on the artery, the cuff pressure is reduced gradually by deflating it. The cuff pressure when the heartbeat is first heard as a soft tapping sound through the stethoscope gives us the systolic pressure.
(iii) The cuff pressure is reduced further by deflating it more and more. The cuff pressure when the tapping sound in the stethoscope just disappears, gives us the diastolic pressure.
The above observations can be explained as follows: When a high pressure of about 200 mm Hg is applied to the arm by the cuff, then the brachial artery gets closed fully, and hence no blood flows in it. Since no blood flows in the brachial artery at this stage, therefore, no tapping sound is heard in the stethoscope. When the cuff pressure is reduced and becomes equal to the systolic pressure, then the brachial artery opens up slightly and there is an intermittent blood flow in it due to which a soft tapping sound just begins to be heard in the stethoscope. And finally, when the cuff pressure is reduced further and it becomes equal to diastolic pressure, then the brachial artery opens up fully, the blood flow in it is fully restored and hence the tapping sound just disappears.
How do Food and Oxygen Reach Body Cells
We have studied that blood carries food and oxygen around the body. But blood never comes in contact with body cells. So, how do food and oxygen get from the blood to the body cells where they are needed? This happens with the help of plasma which leaks from the blood capillaries around the body cells. This plasma which leaks out from the blood capillaries is called tissue fluid. We can now say that: The liquid from the blood which is forced out through the capillary walls and moves between all the body cells (providing them with food and oxygen and removing carbon dioxide) is called tissue fluid.
Actually, the walls of blood capillaries are very thin. So, when blood flows through the capillaries, a liquid called tissue fluid leaks from the blood capillaries and goes into tiny spaces between the various body cells in the tissues. The tissue fluid carries food and oxygen from the blood to the cells and picks up its waste products like carbon dioxide. After doing its job, most of the tissue fluid seeps back into blood capillaries.
The remaining tissue fluid carrying large protein molecules, digested fat, germs from the cells, and fragments of dead cells, enters into another type of tiny tube called lymph capillaries and it becomes lymph. This lymph (alongwith its contents) is returned to the blood by a different kind of transport system in the human body called the lymphatic system. We will now describe the lymphatic system in brief.
Lymphatic System: Parts & Common Problems
A system of tiny tubes called lymph vessels (or lymphatics) and lymph nodes (or lymph glands) in the human body which transports the liquid called lymph from the body tissues to the blood circulatory system is called the lymphatic system. The lymphatic system consists of the following parts:
- Lymph capillaries
- Larger lymph vessels
- Lymph nodes (or Lymph glands)
- Lymph
Lymph capillaries are tiny tubes that are present in the whole body (just like blood capillaries) (see Figure 99). Lymph capillaries, however, differ from blood capillaries in two ways: lymph capillaries are closed-ended (the end of lymph capillaries in the tissues of the body is closed), and the pores in the walls of lymph capillaries are bigger in size (than that of blood capillaries). Since the ends of the lymph capillaries in the body tissues are closed, the tissue fluid can only seep into the walls of the lymph capillaries present in the body tissues. Moreover, since the pores in the walls of the lymph capillaries are somewhat bigger, so even large protein molecules present in the tissue fluid can enter into lymph capillaries (which could not pass into blood capillaries).
The lymph capillaries join to form larger lymph vessels. The lymph vessels have lymph nodes (or lymph glands) at intervals. The lymph nodes contain a special type of cells called lymphocytes. Lymph nodes containing lymphocytes are involved in the cleaning of lymph and protecting the body from disease. The lymph vessels are connected to large veins of the blood circulatory system.
Lymph is a light yellow liquid that is somewhat similar in composition to blood plasma. Lymph is not red like blood because it does not contain red blood cells. Lymph contains large protein molecules and digested food (which come into it from the tissue fluid between the cells). It also contains germs from the cells and fragments of dead cells. Lymph is another medium of circulation in the human body. But lymph flows in only one direction from body tissues to the heart. Since lymph is derived from the tissue fluid which remains outside the cells of the body, it is also called extracellular fluid. Lymph contains a special type of white blood cells called lymphocytes which help in fighting infection and disease.
Lymph containing large protein molecules, digested fat, germs, and fragments of dead cells from the tissue fluid around the body cells seeps into the lymph capillaries present throughout the body. From lymph capillaries, lymph passes into larger lymph vessels containing lymph nodes. In the lymph nodes, lymph is cleaned by white blood cells called lymphocytes. These white blood cells eat the germs and dead cells and also make antibodies for protecting the body from disease. The cleaned lymph containing large protein molecules, digested fat, and other useful materials is transported by lymph vessels to the large veins (called subclavian veins) which run just beneath the collar bone. These veins carry the lymph to the heart. In this way, the circulation of lymph from the body tissues to the heart is completed.
Lymphocytes are a special type of white blood cells. In this micrograph, lymphocytes have been stained (colored with a dye) so that they can be seen clearly.
Functions of Lymph (or Lymphatic System)
- The lymph (or lymphatic system) takes part in the nutritive process of the body.
- For example, it puts into circulation large protein molecules by carrying them from the tissues into the bloodstream (which could not be absorbed by blood capillaries due to their large size).
- Lymph also carries digested fat for the nutritive process.
- Lymph (or lymphatic system) protects the body by killing the germs drained out of the body tissues with the help of lymphocytes contained in the lymph nodes, and by making antibodies.
- Lymph (or lymphatic system) helps in removing the waste products like fragments of dead cells, etc.